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J Comp Pathol. 2000 Aug-Oct;123(2-3):226-9.
Desquamative form of cryptogenic fibrosing alveolitis in a cat.

Rhind SM, Gunn-Moore DA.

Department of Veterinary Pathology, The University of Edinburgh, Roslin, Midlothian, EH25 9RG, UK.

Bronchopulmonary disease is not uncommon in cats, many cases falling into the categories of chronic bronchitis and the "feline asthma syndrome". We report a case of chronic bronchopulmonary disease in an adult cat, which was initially diagnosed as chronic bronchitis. Failure to respond to appropriate therapy led to euthanasia. At necropsy, the lungs exhibited multifocal areas of consolidation, especially at the periphery of the diaphragmatic lobes. Histopathological examination revealed a striking variability of lesions, with interstitial fibrosis and intra-alveolar accumulations of macrophages in addition to alveolar epithelialization and smooth muscle hyperplasia. These changes were consistent with those described for the desquamative form of cryptogenic fibrosing alveolitis in human beings. 2000 Harcourt Publishers Ltd.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11032682&dopt=Abstract

Int J Epidemiol. 2000 Oct;29(5):862-70.
Effect of outdoor and indoor nitrogen dioxide on respiratory symptoms in schoolchildren.

Shima M, Adachi M.

Department of Public Health, Chiba University School of Medicine, Chiba 260-8670, Japan. simed.m.chiba-u.ac.jp

BACKGROUND: Nitrogen dioxide (NO(2)), an oxidant gas that contaminates both outdoor and indoor air, is considered to be a potential risk factor for asthma. We investigated concurrently the effects of outdoor and indoor NO(2) on the prevalence and incidence of respiratory symptoms among children. METHODS: A cohort study was carried out over 3 years on 842 schoolchildren living in seven different communities in Japan. Indoor NO(2) concentrations over 24 hours were measured in both winter and summer in the homes of the subjects, and a 3-year average of the outdoor NO(2) concentration was determined for each community. Respiratory symptoms were evaluated every year from responses to questionnaires. RESULTS: The prevalence of bronchitis, wheeze, and asthma significantly increased with increases of indoor NO(2) concentrations among girls, but not among boys. In neither boys nor girls were there significant differences in the prevalence of respiratory symptoms among urban, suburban, and rural districts. The incidence of asthma increased among children living in areas with high concentrations of outdoor NO(2). Multiple logistic regression analysis showed that a 10 parts per billion (ppb) increase of outdoor NO(2) concentration was associated with an increased incidence of wheeze and asthma (odds ratios [OR] = 1.76, 95% CI : 1.04-3.23 and OR = 2.10, 95% CI : 1.10-4.75, respectively), but that no such associations were found with indoor NO(2) concentration (OR = 0.73, 95% CI : 0.45-1.14 and OR = 0.87, 95% CI : 0.51-1.43, respectively). CONCLUSIONS: These findings suggest that outdoor NO(2) air pollution may be particularly important for the development of wheeze and asthma among children. Indoor NO(2) concentrations were associated with the prevalence of respiratory symptoms only among girls. Girls may be more susceptible to indoor air pollution than boys.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11034970&dopt=Abstract

Public Health. 2000 Sep;114(5):328-9.
Small area variation in hospital admission: random or systematic?

Twigger JP, Jessop EG.

West Surrey Health Authority, The Ridgewood Centre, Old Bisley Road, Camberley, Surrey GU16 5QE, UK.

For some conditions hospital admission is mandatory. This should lead to low variability in admission rates and no effect on admission rate of distance from hospital. If admission is discretionary, we would expect high variability in small area admission rates, and a decline in admission rate as travel time to hospital increases. We wanted to see if non-random variability of admission rates, as measured by the systematic coefficient of variation (SCV), and distance decay, as estimated in regression models, were related. We examined variability and travel time dependence of hospital admission for seven conditions in 62 small (mean population 9900) areas of Surrey, England. Age and sex standardized admission ratios (SAR) were calculated, and their dependence on travel time, adjusting for deprivation, were estimated by linear multiple regression adjusted for spatial correlation. Deprivation was measured by Jarman's score, and time by computerized estimates of drive time to the nearest acute hospital. We found an inverse relationship between time to hospital and admission ratio for ischaemic heart disease, bronchopneumonia and chronic bronchitis. Admission ratios for diabetes mellitus and stroke were related to neither deprivation nor time. For these seven conditions there was no simple relationship between SCV and travel time dependence.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11035450&dopt=Abstract

Med J Malaysia. 2002 Sep;57(3):340-7.
Respiratory conditions in Malaysian asbestos cement workers.

Lim HH, Rampal KG, Joginder S, Bakar CM, Chan KH, Vivek TN.

Department of Community Medicine, Universiti Kebangsaan Malaysia.

A cross-sectional study was conducted to determine the prevalence and type of respiratory conditions including asbestos-related diseases among Malaysian asbestos cement workers. The study population consisted of 1164 workers who had undergone medical surveillance from 1995 to 1997, including full history, physical examination, chest radiography and spirometry. More than half the male workers were smokers or ex-smokers, with smokers having more respiratory symptoms and signs, and reduced FEV1 compared with non smokers. The five most common respiratory conditions diagnosed were bronchial asthma, chronic bronchitis, pulmonary tuberculosis, upper respiratory tract infections and allergic rhinitis. On follow-up, there were also two cases of asbestosis and one case of bronchial carcinoma. The asbestosis cases were probably related to heavy occupational exposure to asbestos fibres in the past, before governmental regulations were gazetted in 1986. Further follow-up is essential for continued monitoring of the health status of asbestos workers.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12440274&dopt=Abstract

Due to the complexity , the biological process of hair growth is still a work in progress. Nonetheless, several therapeutic methods including prescription medications, transplant surgery, nutritional suppelements, and even snake oils have been in use to help those who attempt to restore their hair. None of these approaches are perfect due to the heterogeneity in the causes that underlie hair loss. Unfortunately, most of these chemical drugs and hair transplantation operations are accompanied by undesirable side effects.

Hair Million of Dream Pharm provides an alternative approach to hair loss problems. Numerous anecdotal cases have demonstrated that this herbal formula based on the authentic Chinese herbs from Chinese Pharmacopoeia actually improves the age-related hair thinning and hair loss among a significant fraction of people who take it as suggested. We still do not understand the mechanisms of action as to how Hair Million works to stop hair loss and promote hair growth, despite all the positive anecdotal demonstration. Neither scientific research nor placebo controlled clinical analysis has been conducted due to the high cost of such trials. Lack of scientific/clinical research is quite common in herbal arena. Just because science hasn't scrutinized doesn't mean we should stop taking daily food and herbal supplements altogether: our life must go on until we have better understandings of food and herb that we have been taking generation after generation. There are two merits in this hair restoration herbal formula: Firstly, Hair Million is relatively inexpensive compared with other methods, and secondly, it is made of edible herbs that are known to be safe when consumed in regular quantities.

DHEA is a natural hormone, and it is produced in our body by the adrenal glands. DHEA has been suggested to provide numerous potential benefits. DHEA (or dehydroepiandrosterone) is converted into androgens (male hormones) or estrogens (female hormones) in the cells.

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