DreamPharm Products:
Lutein-20||Herbs for headache, fever, and migraine ||
Milk thistle||Saw palmetto||
Triple B Super Vision||Garlic, Ginger, and Grapeseed Extract||
Ginseng and Ginkgo||Hair Million||
DHEA||Coenzyme Q10||
Sleep Aid herbal formula - natural sleep aid||Herbal Breath - herbs for bad breath problems.||
Weight loss herbal formula||Ginkgo biloba||
Colon cleansing, Laxative for constipation relief, laxative, and colon cleansing||ViaVita, Lecithin for healthy liver
Interferon research abs 1 ||
Hemoglobin research abs ||
Stem cell research abs ||
Nucleic acid research abs ||
Herpes research abs ||
Bronchitis research abs ||
Schizophrenia research abs ||
Tuberculosis research abs ||
Pneumonia research abs ||
Constipation research abs ||
Laxative research abs ||
hair research abs ||
hair related research references ||
testosterone related research references ||
melanin related research references ||
caffeine related research references ||
nicotine related research references
Heart Dis. 2003 Jul-Aug;5(4):253-71.
Cardiovascular manifestations of substance abuse: part 2: alcohol, amphetamines, heroin, cannabis, and caffeine.
Frishman WH, Del Vecchio A, Sanal S, Ismail A.
Department of Medicine, The New York Medical College/Westchester Medical Center, Valhalla, NY 10595, USA.
The abuse of alcohol is associated with chronic cardiomyopathy, hypertension, and arrhythmia. Abstinence or using alcohol in moderation can reverse these cardiovascular problems. Alcohol is also distinguished among the substances of abuse by having possible protective effects against coronary artery disease and stroke when used in moderate amounts. Amphetamines (eg, speed, ice, ecstasy) have many of the cardiovascular toxicities seen with cocaine, including acute and chronic cardiovascular diseases. Heroin and other opiates can cause arrhythmias and noncardiac pulmonary edema, and may reduce cardiac output. Cardiovascular problems are less common with cannabis (marijuana) than with opiates, but major cognitive disorders may be seen with its chronic use. It is still controversial whether caffeine can cause hypertension and coronary artery disease, and questions have been raised about its safety in patients with heart failure and arrhythmia.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12877759&dopt=Abstract [PubMed - in process]
Am J Physiol Cell Physiol. 2003 Jul 23 [Epub ahead of print].
Partial inhibition of SERCA is responsible for extracellular Ca2+ dependency of AlF4--induced [[!LB]]Ca2+[[!RB]]i oscillations in rat pancreatic acinar cells.
Chong SA, Hong SY, Moon SJ, Park JW, Hong JH, An JM, Lee SI, Shin DM, Seo JT.
Department of Oral Biology & Oral Science Research Center, BK21 Project for Medical Science, Yonsei University College of Dentistry, Seoul, Korea, Republic of.
AlF4(-) is known to generate [Ca(2+)]i oscillations by activating G-proteins in many cell types. However, in rat pancreatic acinar cells, AlF4(-)-evoked [Ca(2+)]i oscillations were reported to be dependent on extracellular Ca(2+), which contrasts with the [Ca(2+)]i oscillations induced by cholecystokinin (CCK). Therefore, we investigated the mechanisms by which AlF4(-) generates extracellular Ca(2+)-dependent [Ca(2+)]i oscillations in rat pancreatic acinar cells. AlF4(-)-induced [Ca(2+)]i oscillations were stopped rapidly by the removal of extracellular Ca(2+) and were abolished upon the addition of 20 mM caffeine and 2 micro M thapsigargin, indicating that Ca(2+) influx plays a crucial role in the maintenance of the oscillations and that an IP3-sensitive Ca(2+) store is also required. The amount of Ca(2+) in the intracellular Ca(2+) store was found to decrease as the AlF4(-)-induced [Ca(2+)]i oscillations continued. Measurement of (45)Ca(2+) influx into isolated microsomes revealed that AlF4(-) directly inhibited sarco/endoplasmic reticulum Ca(2+) ATPase (SERCA). The activity of plasma membrane Ca(2+) ATPase (PMCA) during AlF4(-) stimulation was not significantly different from that during CCK stimulation. After the partial inhibition of SERCA with 1 nM thapsigargin, 20 pM CCK-evoked [Ca(2+)]i oscillations were found to be dependent on extracellular Ca(2+). This study shows that AlF4(-) induces [Ca(2+)]i oscillations probably by IP3 production via G-protein activation but that these oscillations are strongly dependent on extracellular Ca(2+) due to the partial inhibition of SERCA.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12878491&dopt=Abstract [PubMed - as supplied by publisher]
Naunyn Schmiedebergs Arch Pharmacol. 2003 Aug;368(2):113-8. Epub 2003 Jul 17.
Interactive role of adenosine and dopamine in the opiate withdrawal syndrome.
Stella L, De Novellis V, Vitelli MR, Capuano A, Mazzeo F, Berrino L, Rossi F, Filippelli A.
Department of Experimental Medicine, Section of Pharmacology "Leonardo Donatelli", Faculty of Medicine and Surgery, Second University of Naples, Via Costantinopoli 16, 80138, Naples, Italy, luigistellreemail.it
Adenosine reduces opioid withdrawal symptoms by activating A(1) adenosine receptors, probably by inhibiting excitatory amino acid release. Since blockade of A(2A) adenosine receptors seems to enhance dopaminergic striatopallidal transmission, we evaluated the role of the purinergic system in the opiate withdrawal syndrome by using two A(1) receptor agonists [ N(6)-cyclohexyladenosine, CHA and 2-chloro- N(6)-cyclopentyladenosine, CCPA], and two A(2A) receptor antagonists (SCH 58261 and 8-(3-chlorostyryl)caffeine, CSC).Male adult rats received increasing doses of morphine sulphate suspended in 5 ml/kg of a sustained release preparation (40-100 mg/kg s.c.) daily for 4 days and 20 h after the last administration, the withdrawal syndrome was evoked by naloxone (5 mg/kg i.p.). Animals were observed for 30 min for signs of opiate withdrawal. Other groups of rats were implanted with concentric probes for microdialysis and dopamine levels were measured in the nucleus accumbens. CHA and CCPA (0.05, 0.1 or 0.5 mg/kg i.p.) significantly reduced "wet-dog" shakes, diarrhoea, teeth chattering, jumping and writhing. SCH 58261 and CSC (0.1, 0.5 or 1 mg/kg i.p.), given 10 min before naloxone, also reduced signs of opiate withdrawal. CHA plus SCH 58261 and CCPA plus CSC greatly enhanced the reduction of withdrawal signs observed with CHA and CCPA or CSC and SCH 58261 alone. In vivo microdialysis showed that naloxone significantly decreased DA release; this effect was prevented by pretreatment with systemic SCH 58261 and CSC, but not with CHA and CCPA. Our results demonstrate that A(1) and A(2A) adenosine receptors mediate the effect induced by adenosine in opiate withdrawal syndrome and suggest that adenosine A(1) agonists and adenosine A(2A) antagonists may be beneficial in the treatment of this syndrome.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12879207&dopt=Abstract [PubMed - in process]
Vitamins, amino acids, oils for topical application, and prescription medications...
There are a number of approaches to hair loss problems.
Hair Million is an herbal alternative. It is a formula made of traditional, edible herbs
and has been anecdotally demonstrated the efficacy to ward off hair loss
problems.
There is no singular medical or alternative cure for hair loss since the
biology of hair growth is a highly complicated phenomenon.
It is unknown how Hair Million stops hair loss,
and promotes hair restoration.
The advantages of Hair Million over other approaches are, firstly, Hair Million is comparatively inexpensive,
and secondly, it is made only of traditionally used safe and healthy herbs that promote hair growth
according to Chinese pharmacopoeia. In addition, Hair Million is cardiotonic, meaning that Hair Million consists of herbs
that strengthens your heart, according to Chinese medicine. There is an interesting research paper which correlates baldness
to heart diseases: people with alopecia or hair loss
problems are significantly more likely to develop heart attacks.
DHEA is a natural hormone, and it is produced in our body by the adrenal glands.
DHEA has been suggested to provide numerous potential benefits. DHEA (or dehydroepiandrosterone) is converted into androgens (male hormones)
or estrogens (female hormones) in the cells.
DreamPharm Online Healthy Supplements ||
Lutein ||
Progesterone Cream ||
Natural herbal formula for hair loss problems ||