DreamPharm Products:
Lutein-20||Herbs for headache, fever, and migraine ||
Milk thistle||Saw palmetto||
Triple B Super Vision||Garlic, Ginger, and Grapeseed Extract||
Ginseng and Ginkgo||Hair Million||
DHEA||Coenzyme Q10||
Sleep Aid herbal formula - natural sleep aid||Herbal Breath - herbs for bad breath problems.||
Weight loss herbal formula for menopause and pms||Ginkgo biloba||
Colon cleansing, Laxative||ViaVita, Lecithin for healthy liver
Fatty acids resources:
Pathogen research abs 1 || Pathogen research abs 2 || Pathogen research abs 3 || Pathogen research abs 4 || Pathogen research abs 5 ||
Hormone and endocrine research abs 1 || Hormone and endocrine research abs 2 || Hormone and endocrine research abs 3 || Hormone and endocrine research abs 4 || Hormone and endocrine research abs 5
J Am Med Dir Assoc. 2000 Jan-Feb;1(1):25-28.
Prevalence of Hypothyroidism in a Southeastern Nursing Home.
Thong H, Rahimi AR.
Department of Internal Medicine Education, Division of Geriatrics, Memorial Health University Medical Center, Savannah, GA, and Mercer University School of Medicine, Savannah Campus.
ABSTRACT BACKGROUND: It is common to find older patients who have received thyroid hormone replacement for years without clear-cut documentation of hypothyroidism. The diagnosis of hypothyroidism in older patients presents a difficult problem. OBJECTIVE: We sought to determine the prevalence of hypothyroidism and the sensitivity of clinical determinants for hypothyroidism during withdrawal of thyroid hormone therapy (vital signs, weight, MMSE, and depression scale) in a nursing home population. METHODS: We studied a cohort of patients in two nursing centers in southeast Georgia. Those receiving thyroid hormone without documented hypothyroidism had complete a physical examination and serum TSH, MMSE,depression scale assessment at baseline and 3 and 6 weeks after discontinuation of thyroid therapy. Weights and vital signs were monitored throughout the study. The hypothyroid state was defined by an attending physician by clear documentation of elevated TSH > 10 &mgr;IU/mL and clinical manifestation of hypothyroidism. RESULTS: Thirteen of 129 patients were receiving thyroid supplement; seven had documented hypothyroidism. Five of the six without documented hypothyroidism completed the study. Three of those five were found to be hypothyroid (TSH: 69.4-110.4 &mgr;IU/mL at 6 weeks of thyroid therapy). Among the clinical determinants, only weight correlated with elevated TSH and hypothyroidal state. At 6 weeks, the other two patients had borderline elevation of TSH, and one patient normalized at 4 months. Both had negative antimicrosomal antibodies and were considered euthyroid. CONCLUSIONS: The prevalence of true hypothyroidism ranged from 6.2% to 7.8%. We identified unnecessary therapy in two of 13 patients. Increased weight was the most sensitive indicator of evolving hypothyroidism.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12818044&dopt=Abstract [PubMed - as supplied by publisher]
Endokrynol Diabetol Chor Przemiany Materii Wieku Rozw. 2000;6(2):79-92.
[Serum levels of adhesion molecules (sICAM-1, sVCAM-1 and sP-selectin) in children and adolescents with thyroid diseases]
[Article in Polish]
Bossowski A, Urban M, Citko A, Sobotko J, Bossowska A.
II Klinika Chorob Dzieci AM w Bialymstoku.
The targeting and recruitment of inflamatory cells to vascular endothelium in Graves' disease (GD) is mediated by intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and P-selectin. The aim of this study was to estimate the serum concentrations of soluble (sICAM-1), soluble (sVCAM-1) and soluble (sP-selectin) in patients with (GD) (n=44, mean age 14.8 years), with nontoxic nodular goiter (NTNG) (n=36, mean age 15.6 years) and in a group of healthy controls (n=20, mean age 14.5 years). ELISA method was used to determine the concentrations of adhesion molecules and antithyroglobulin and antithyroid peroxidase antibodies in patients with thyroid diseases. The anti-TSH receptor autoantibodies (TRAbs) were evaluated using a radio receptor assay (RRA). The serum levels of sICAM-1,sVCAM-1 and sP-selectin were markedly elevated in patients with GD before treatment with methimazole (p<0.0001 for all) and after 8 weeks of therapy (p<0.001 for sICAM-1 and sVCAM-1, p<0.014 for sP-selectin). After 24 months of therapy, serum concentrations of sVCAM-1 and sP-selectin were normalized, whereas serum level of sICAM-1 remained elevated. Futhermore, patients with NTNG showed a slighty elevated sICAM concentration. Serum levels of sICAM-1,sVCAM-1 and sP-selectin in patients with GD correlated with the serum concentrations of triiodothyronine (r=0.42, 0.45; 0.42, respectively) and thyroxine (NS, r=0.39; 0.46, respectively). Moreover, we observed a positive correlation between serum levels of TPO-Abs, TG-Abs, TRAbs and sICAM-1 (r=0.51; 0.40; 0.41 respectively) and sVCAM-1 (r=0.49; 0.38; 0.52, respectively). However, in patients with NTNG no correlation between serum level of adhesion molecules or thyroid hormones and serum level of antithyroid antibodies, respectively, was found. We conclude that the antithyroid antibodies involved in the pathogenesis of Graves' disease cause the elevation of the levels of adhesion molecules, which act as mediators of lymphocyte inflow and adhesion to the tissue of the thyroid gland. The evaluation of the serum level of soluble forms of adhesion molecules in children and adolescents with hyperthyroidism allows control over the autoimmune process.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12818068&dopt=Abstract [PubMed]
Endokrynol Diabetol Chor Przemiany Materii Wieku Rozw. 2000;6(2):129-34.
[The role of galanin in the endocrine system]
[Article in Polish]
Zdrojewicz Z, Sowinska E, Sztuka-Pietkiewicz A.
Katedra i Klinika Endokrynologii i Diabetologii AM we Wroclawiu.
Galanin, a 29-30 amino-acid neuropeptide is distributed in the central and peripheral nervous systems, the pituitary gland, the gastrointestinal tract and also in the pancreas. The endogenous and exogenous effects of galanin are mediated by three receptor subtypes, which are termed: GALR1, GALR2, and GALR3. Galanin has a significant role in physiological and pathological processes in adults as well as in children. It has an ability to contract smooth musles in GI (facilitation and inhibition), stimulates reflexes in the CNS, decreases pancreatic amylase secretion, changes transport of electrolytes Na+ and CL-. It takes part in etiopathogenesis of depression, Alzheimer's disease and diarhoea, exerts tonic inhibition of nociceptive input to the central nervous system and regulates a function of hypothalamic-pituitary system. Galanin decreases insulin and somatostatin secretion, increases glucagon secretion, takes part in prolactin release, stimulates growth hormone-releasing hormone, hypothalamic gonadotropin releasing hormone and corticotropin releasing hormone. It causes increase of somatotropin secretion, luteinizing hormone and foliculotropin release and adrenocorticotropin secretion. The hypothalamic galanin takes part in etiopathogenesis of obesity not only in human reproductive period, but also in adolescence, increasing the apetite and changing fat metabolism. This variety of actions emphasizes the potential importance of this peptide in the regulation of cells function and the need to understand the mechanism by which they act.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12818074&dopt=Abstract [PubMed]
Endokrynol Diabetol Chor Przemiany Materii Wieku Rozw. 2000;6(1):45-50.
[Physiopathological implications of thyroid function in premature infants]
[Article in Polish]
Korman E.
Klinika Endokrynologii i Diabetologii Wieku Rozwojowego Instytutu Pediatrii AM w Poznaniu.
The last two decades have been characterized by a remarkable improvement of the methods used for the determination of thyroid hormones concentration as well as by mass screening of congenital hypothyroidism. This has resulted in an expanded knowledge on the development of the hypothalamus-hypophysis-thyroid function in the fetus and in newborn. The paper presents the latest advancements in this field. The following thyroid dysfunction syndromes in premature infants are discussed: transient hypothyroxinemia, transient primary hypothyroidism, transient idiopathic hyperthyrotropinemia, low T3 - syndrome. All these conditions should be taken into consideration while determining the thyroid function in premature infants, particularly while screening newborns with congenital hypothyroidism.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12818084&dopt=Abstract [PubMed]
Int J Cancer. 1999 May 5;81(3):339-44.
Breast-cancer risk following long-term oestrogen- and oestrogen-progestin-replacement therapy.
Magnusson C, Baron JA, Correia N, Bergstrom R, Adami HO, Persson I.
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden. Cecilia.Magnussoep.ki.se
While use of hormone-replacement therapy (HRT) effectively alleviates menopausal symptoms and prevents osteoporosis and possibly cardiovascular disease, there is concern of a detrimental impact on breast-cancer risk. There is a particular lack of data regarding the effect of long-term use of oestrogen-progestin combinations on breast-cancer risk. We conducted a large epidemiological study in Sweden, where combined oestrogen-progestin treatment has been predominant, to examine the influence of different regimens of menopausal hormone therapy on breast-cancer risk. In this population-based case-control study, 3,345 women aged 50 to 74 years with invasive breast cancer (84% of all eligible) and 3,454 controls of similar age (82% of all selected) were included. Mailed questionnaires and telephone interviews were used to collect detailed information on use of hormone replacement and on potential confounding factors. Odds ratios (OR) and 95% confidence intervals (CI) were estimated through multiple logistic regression. There was a trend of increasing breast-cancer risk with duration of oestrogen/oestrogen-progestin use (OR for women treated at least 10 years, 2.43; 95% CI, 1.79-3.30, as compared to never-users), with statistically significant estimates only for women with BMI<27 kg/m2. Excess risks were observed to current use and use that ceased more than 10 years ago (OR for women treated at least 5 years, OR was 2.68, 95% CI, 2.09-3.42, and OR 2.57, 95% CI, 1.28-5.15, as compared with never-users, respectively). A positive association which was noted for use of oestrogen combined with testosterone-derived progestins appeared especially pronounced with continuously combined regimens. Long-term use of replacement oestrogens with or without progestins may substantially increase the incidence of post-menopausal breast cancer, particularly among non-obese women.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10209946&dopt=Abstract
Concerned about losing hair? Hair loss and baldness is indeed a visible problem, and
could be more than just the matter of change in appearance.
Saw palmetto berry is a widely known herbal supplement for hair loss problems.
However, there are a number of great anecdotal herbs that people used for thousands of years stop hair loss and
start hair growth.
Numerous anecdotal cases have demonstrated that this herbal formula based on Chinese herbs actually improves the age-related hair thinning and hair loss
for a significant fraction of people who take it diligently. It is unknown how Hair Million herbs actually stop hair loss, and promote hair growth,
No scientific research or placebo controlled clinical trials have been conducted. Nonetheless, a number of people agree that it works.
DHEA is a natural hormone, and it is produced in our body by the adrenal glands.
DHEA has been suggested to provide numerous potential benefits. DHEA (or dehydroepiandrosterone) is converted into androgens (male hormones)
or estrogens (female hormones) in the cells.
Our bodies produce decreasing amount of DHEA as we get older.
various health benefits: To deter aging,
improve sexual function/erectile dysfunction, treat cognitive decline, enhance athletic performance,
facilitate weight loss, improve strength, prevent osteoporosis, enhance immunomodulation for rheumatic conditions,
and treat depression.
DreamPharm Online Healthy Supplements ||
Constipation relief, laxative, colon cleansing ||
Lutein ||
Progesterone Cream ||
Natural herbal formula for hair loss problems ||