DreamPharm Products:
Lutein-20||Herbs for headache, fever, and migraine ||
Milk thistle||Saw palmetto||
Triple B Super Vision||Garlic, Ginger, and Grapeseed Extract||
Ginseng and Ginkgo||Hair Million||
DHEA||Coenzyme Q10||
Sleep Aid herbal formula - natural sleep aid||Herbal Breath - herbs for bad breath problems.||
Weight loss herbal formula for menopause and pms||Ginkgo biloba||
Colon cleansing, Laxative||ViaVita, Lecithin for healthy liver
Fatty acids resources:
Pathogen research abs 1 || Pathogen research abs 2 || Pathogen research abs 3 || Pathogen research abs 4 || Pathogen research abs 5 ||
Hormone and endocrine research abs 1 || Hormone and endocrine research abs 2 || Hormone and endocrine research abs 3 || Hormone and endocrine research abs 4 || Hormone and endocrine research abs 5
Lupus. 2003;12(3):222-30.
Circulating human plasmacytoid dendritic cells are highly sensitive to corticosteroid administration.
Shodell M, Shah K, Siegal FP.
Section of HIV Medicine, Department of Medicine, Saint Vinces Catholic Medical Center/Manhattan, New York, NY 10011, USA.
Plasmacytoid dendritic cells (pDC), the major interferon-producing cell type found in human blood, have been implicated in the pathogenesis of systemic lupus erythematosus (SLE). Previous studies in SLE have shown substantial deviations from normal in this minor but immunologically important leukocyte population. Many of the lupus patients studied were receiving corticosteroids. To determine the effects of steroid administration on pDC in healthy adults, four volunteers were given prednisone, 15-30 mg daily, for 4 days. Both counts of pDC, and their ability to produce IFN-alpha were significantly reduced (P = 0.02 and 0.004, respectively) during steroid administration, and rapidly recovered after discontinuation of the hormones. The overall reduction in pDC-derived IFN appeared to be attributable to falls of both number of circulating cells and of IFN produced per pDC. The effects observed with pDC were comparable in magnitude but opposite in direction to that observed for granulocytes. In contrast other blood leukocytes were little affected during steroid therapy.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12708787&dopt=Abstract
J Clin Invest. 1975 Jun;55(6):1237-44.
Hepatic mitochondrial function in ketogenic states. Diabetes, starvation, and after growth hormone administration.
DiMarco JP, Hoppel C.
The study was designed to evaluate hepatic mitochondrial function during ketotic states. The ketogenic models studied were streptozotocin-induced diabetic ketoacidosis, 48 h of starvation, and after growth hormone administration. In the last-mentioned model we observed increased free fatty acids but not ketonemia. Oxidative phosphorylation was measured using the citric acid cycle substrates pyruvate and succinate, the amino acid glutamate, a ketone body beta-hydroxybutyrate, and a long-chain fatty acid palmitoyl-l-carnitine. State 3 (ADP stimulated) and state 4 (ADP limited) respiration, respiratory control ratio (state 3/state 4), and the ADP/O ratios were normal in the controls and the experimental groups. Uncoupled respiration produced by dinitrophenol with a variety of substrates was unchanged in the experimental groups compared to the controls. Fatty acid oxidation was studied in detail. The rate of utilization of palmitoyl-l-carnitine by controls or experimental groups did not depend on the product formed (citrate, acetoacetate). No significant changes were observed in the oxidation of palmitoyl-CoA (+ carnitine) or with an intermediate-chain fatty acid hexanoate. The specific activity of hepatic mitochondria carnitine palmitoyltransferase did not change in any of the three experimental groups. It is concluded that during diabetic ketoacidosis, starvation, and growth hormone administration, there is (a) no alteration in hepatic mitochondrial function; (b) no change in the intrinsic capacity of hepatic mitochondria to oxidize fatty acids; and (c) no change in the specific activity of mitochondrial carnitine palmitoyltransferase. The mechanism by which the body restrains flux through the mitochondrial oxidative machinery remains to be fully determined.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=124319&dopt=Abstract
J Endocrinol. 1975 Mar;64(3):485-502.
Metabolic clearance rate, production rate and mammary uptake of progesterone in the goat.
Heap RB, Bedford CA, Linzell JL.
The dynamics of progesterone uptake and metabolism in the mammary gland of the goat have been measured and related to the metabolic clearance rate and production rate of the hormone determined by tracer kinetic techniques. The metabolic clearance rate of progesterone from blood was 3-13 plus or minus 0-35 (S.E.M.) 1/min in ten experiments on six goats; values tended to be slightly higher in pregnant than in non-pregnant goats. The production rate of progesterone at oestrus, and at day 3 of the normal cycle, was less than 0-01 mug/min. During the luteal phase of the oestrous cycle the production rate was 8-5 and 14-6 mug/min in 2 animals, and in the second half of pregnancy, 15-3 plus or minus 0-6 mug/min (5 animals). Progesterone was extracted from the circulation by the mammary gland of conscious goats with an efficiency of 49-4 plus or minus 11-3% in non-pregnant, and 51-7 plus or minus 11-5% in pregnant aniamals. The mean clearance rate of progesterone by the udder was 0-279 1/min, 8-8% of the metabolic clearance rate. Mammary uptake of progesterone in goats with an actively secreting corpus luteum was 0-64 plus or minus 0-29 mug/min, which gave an estimated value of 0-11-1-88 ng/min/g mammary gland. The mammary extraction of progesterone was investigated in a goat 3 days after oestrus when any high affinity receptor sites would presumably be unoccupied. During the infusion of progesterone into a mammary artery, tissue sample were taken from various organs, including the mammary gland, and the concentration of labelled compounds at steady state was determined. A high mammary extraction of progesterone was found to be determined. A high mammary extraction of progesterone was found to be attributable principally to progesterone metabolism. The metabolites of progesterone were removed from the gland in venous blood and were not stored to any appreciable extent in mammary tissue. Experiments in vitro confirmed the findings in vivo that mammary tissue metabolized labelled progesterone and also pregnenolone and androstenedione; metabolism of dehydroepiandrosterone, oestradiol-17 beta, oestrone and cortisol was relatively small. Confirmation of our previous finding that the mammary gland of the goat can synthesize progesterone from labelled pregnenolone infused into the gland in vivo, further implicated this organ as an active site of metabolism of certain steroids. The physiological role of steroid metabolism in the mammary gland is discussed.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=124325&dopt=Abstract
Biochim Biophys Acta. 1975 Jun 25;394(2):317-22.
Hormone responsiveness of plasma membrane-bound enzymes in normal and regenerating rat liver.
Leoni S, Luly P, Mangiantini MT, Spagnuolo S, Trentalance A, Verna R.
The hormonal responsiveness of plasma membrane-bound enzymes (Na-+-K-+)-ATPase and adenylate cyclase has been investigated in normal and regenerating rat liver. (Na-+-K-+)-ATPase basal activity is not affected by surgery and only slightly affected by partial hepatectomy; its response to epinephrine and cyclic AMP is decreased only 15 h after hepatectomy. Adenylate cyclase activity of plasma membranes from untreated animals is stimulated by parathyroid hormone and thyroxine; partial hepatectomy increased basal activity as well as the stimulation exerted by the aforementioned hormones, when glucagon and epinephrine sensitivity is essentially unaltered.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=124602&dopt=Abstract
Physiol Bohemoslov. 1975;24(2):105-10.
The changes of thyroglobulin in the lysosomal particles of thyroid during the postnatal period in rats.
Knopp J, Garcia MD, Sedlak J, Faberova A.
The distribution of radioactivity and protein-SH groups was studied in neonatal rats injected with 125-I- in the 15,000 g pellets of thyroid glands to obtain information about the colloid which undergoes phagocytosis by lysosomes. The 15,000 g pellet was solubilized in Triton X--100. The soluble portion was enhanced on the 16th day of age, whereas the portion of the insoluble fraction remained almost unchanged. The content of protein-SH groups in the insoluble fraction decreased with age and was increased in the soluble fraction. The concentration of immunoreactive thyroid stimulating hormone (TSH) in the pituitary and in the blood of rats during ontogenesis was higher on the first day after delivery, then decreased within the first seven days and again markedly increased during the third postnatal week. It was concluded that higher amounts of Triton soluble thyroglobulin occurring during the postnatal period in rats reflects the availability of more substrate, i.e. thyroglobulin for pinocytosis and partially depends upon the TSH level. These findings also support the suggestion on maturation of the pituitary-thyroid system during the postnatal period in rats.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=124879&dopt=Abstract
Sudden, and premature hair loss and
baldness is a problem in many ways.
Baldness is indeed becoming an increasing concern in the current aging society.
It changes personal appearance and identity in social context.
Saw palmetto berry extract is a widely known
herbfor hair loss as well as BPH problems in Western world.
Saw palmetto berry contains phytochemicals that inhibits 5-alpha-reductase that converts
testosterone to DHT.
There are a number of traditional herbs that could stop hair loss
and promotes hair growth.
Numerous personal experiences and anecdotal cases testify that the herbal formula based on the Chinese
herbs improves the situation of the age-related hair thinning and hair loss for a large fraction of people
taking it regularly. It is unknown how Hair Million herbs stop hair loss, and promote hair growth due to
the lack of scientific research and placebo controlled clinical trials.
DreamPharm Online Healthy Supplements ||
Lutein ||
Progesterone Cream ||
Natural herbal formula for hair loss problems ||