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Interferon research abs 1 || Hemoglobin research abs || Stem cell research abs || Nucleic acid research abs || Herpes research abs || Bronchitis research abs || Schizophrenia research abs || Tuberculosis research abs || Pneumonia research abs || Constipation research abs || Laxative research abs







Arch Latinoam Nutr. 2002 Mar;52(1):20-8.
[Effects of secretory and osmotic diarrhea on rats intestinal function and morphology]

[Article in Spanish]

de Lima de Mon M, Cioccia AM, Gonzalez E, Hevia P.

Escuela de Medicina Luis Razetti, Universidad Central de Venezuela (UCV), Laboratorio de Nutricion Universidad Simon Bolivar, Venezuela.

In order to compare intestinal morphology and function, diarrhea was produced in rats using laxatives in the diet. The 14 day study included two groups of rats with diarrhea (osmotic or secretory), two groups without diarrhea but with a degree of malnutrition which was similar to that seen in the rats with diarrhea (malnourished without diarrhea) and a well-nourished group (control). The inclusion of laxatives(lactose or bisoxatin acetate) cause a reduction in food intake, diarrhea an malnutrition. It also caused a reduction in dietary protein and fat digestibility which was proportional to the severity of diarrhea and more pronounced in secretory diarrhea. In the malnourished rats without diarrhea, malnutrition did not affect their absorptive function. Both in the rats with secretory and osmotic diarrhea an intestinal hypertrophy was observed. This hypertrophy was proportional to the severity of diarrhea and independent of its aetiology. In the intestines of the rats with both types of diarrhea there was inflammation, a greater number of mitotic figures but the flattening of the villi seen in the malnourished rats without diarrhea was not seen. In osmotic diarrhea there was, in addition, a patchy damage of the surface of the jejunal mucosa and an increment in the number of goblet cells, indicating a more severe intestinal deterioration. Since despite this greater deterioration, these rats absorbed more protein and fat we concluded that the alterations in intestinal morphology seen in this study was not predictive of intestinal function. The study also showed that diarrhea had a trophic effect on the intestine which did not occur in malnourished rats without diarrhea.


online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12214542&dopt=Abstract



J Anal Toxicol. 2002 Sep;26(6):370-3.
Elevated blood lead levels resulting from the ingestion of air rifle pellets.

Treble RG, Thompson TS.

Saskatchewan Health, Provincial Laboratory, Regina, Canada. rontreblotmail.com

There have been numerous reports of lead poisoning resulting from the ingestion of foreign bodies. A case involving the ingestion of spent air rifle pellets is described. No clinical symptoms were observed, despite the fact that the young child exhibited elevated blood lead levels as high as 2.7 micromol/L (56 microg/dL). X-rays of the child's abdomen confirmed the ingestion of the pellets. The patient was treated with laxatives, and the pellets were successfully passed over the course of the next few days. Prior to release from the hospital, the child's blood lead level had dropped to 1.7 umol/L (35 microg/dL).


online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12220020&dopt=Abstract



Phytomedicine. 2002 Jul;9(5):373-6.
A comparative study between excess-dose users and regular-dose users of rhubarb contained in Kampo medicines.

Mantani N, Kogure T, Sakai S, Kainuma M, Kasahara Y, Niizawa A, Shimada Y, Terasawa K.

Department of Japanese Oriental Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Sugitani. nmantanhowa.gunma-u.ac.jp

With prolonged use of rhubarb-containing Kampo medicines, some patients come to ask for high-dose rhubarb because of deteriorated reactivity to rhubarb. We divided patients into two groups in terms of rhubarb-dose, and compared clinical backgrounds between regular-dose group and excess-dose group. Patients who were treated with rhubarb-containing Kampo extracts (manufactured prescriptions) or Kampo formulae (decoctions) for more than 12 months were enrolled. These two groups were compared for age, sex, shape of stool, abdominal symptoms, existence of hemorrhoids, Kampo diagnosis of abdomen, past stimulant laxative use, duration of stimulant laxative use before the first administration of rhubarb, duration of rhubarb use in our hospital, and initial existence of stimulant pain caused by taking stimulant laxatives for the first time. No significant difference was shown between the two groups in terms of age, duration of stimulant laxative-use before the first prescription of rhubarb, shape of stool, abdominal symptoms, existence of hemorrhoids, or duration of rhubarb-use. However, most patients in the regular-dose group had initial stimulant pain of the abdomen upon taking stimulant laxatives for the first time, but most patients in the excess-dose group did not (p < 0.001). All patients except one in the regular dose group had the sign of "umbilical region tenderness on pressure", but half of the excess-dose group did not have it (p = 0.041). Based on these findings, the absence of "initial stimulant pain" and the absence of "umbilical region tenderness on pressure" may predict increasing or excess use of rhubarb, and long-term use of rhubarb should be discouraged more strongly in the patients without these signs.


online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12222654&dopt=Abstract








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There are a number of traditional herbs that could stop hair loss and promotes hair growth. Numerous personal experiences and anecdotal cases testify that the herbal formula based on the Chinese herbs improves the situation of the age-related hair thinning and hair loss for a large fraction of people taking it regularly. It is unknown how Hair Million herbs stop hair loss, and promote hair growth due to the lack of scientific research and placebo controlled clinical trials.














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