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Interferon research abs 1 || Hemoglobin research abs || Stem cell research abs || Nucleic acid research abs || Herpes research abs || Bronchitis research abs || Schizophrenia research abs || Tuberculosis research abs || Pneumonia research abs || Constipation research abs || Laxative research abs







Uchu Koku Kankyo Igaku. 2000 Sep;37(3):49-56.
[Relaxative effects of supine floating on heart rate, blood pressure and cardiac autonomic nervous [correction of nerveous] system activity]

[Article in Japanese]

Nishimura M, Onodera S.

Graduate School of Medical Professions, Kawasaki University of Medical Welfare, Kurashiki City, Okayama, Japan.

The purpose of this study was to make clear the relaxative effects of supine floating (SF) on heart rate, blood pressure and cardiac autonomic nervous activity in males. Ten males served as subjects (n=10, mean age: 22.4 yrs). All subjects gave informed consent before participating. Water and room temperature were 30 degrees C. Heart rate and blood pressure were measured during SF or control (C) conditions. Cardiac autonomic nerve activity was estimated with the power spectrum analysis of heart rate variability (HRV) by using the Fast Fourier Transformation (FFT). High frequency (HF; 0.15-0.40 Hz) and the ratio of low frequency (LF; 0.04-0.15 Hz) to HF (LF/HF) were used as an indicator of cardiac vagal activity and sympatho-vagal balance, respectively. Those values were showed logarithmically (LogHF and LogLF/LogHF). LogHF during SF condition was significantly increased, LogLF/LogHF, heart rate and blood pressure were significantly decreased. These data indicate that cardiac vagal activity is enhanced and sympathetic nervous activity is suppressed by reciprocal response.


online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12715823&dopt=Abstract



J Pediatr Surg. 2003 May;38(5):819-23.
Combined approach to functional constipation in children.

Amendola S, De Angelis P, Dall'oglio L, Di Abriola GF, Di Lorenzo M.

Digestive Surgery and Endoscopic Unit and the Department of Gastroenterology, Bambino Gesu Children's Hospital, Rome, Italy, and the Department of Surgery, University of Montreal, Ste-Justine Hospital, Montreal, Quebec, Canada.

Background/Purpose: The authors' 15-year experience with children shows a high percentage of recurrence of functional constipation (FC) with conventional treatment. These data, confirmed in the international literature, led them to develop a new therapeutic approach. The aim of this study was to achieve intestinal control and avoid recurrence of FC in children through use of medical-psychological treatment. METHODS: The authors studied 25 children (18 boys; mean age, 4.7 years; range, 2.10 to 7), 20% of whom had anal fissure, 30% retentive soiling, 52% pain on defecation, and 88% fecal retention owing to FC. Children and parents were questioned about eating and sleeping habits, school, toilet training, and daily routine. Treatment included increasing water and fiber intake, laxatives, and family therapy including making rules and working on autonomy and paternal role. RESULTS: Mean onset of FC was 3.5 years, after "stressful events" in 88%. The questionnaire shows that 68% lacked parental autonomy and authority; 84% of children decided on their own about eating habits and sleeping; 68% had a "peripheral" father with a mother-child symbiotic relationship. After one month of therapy, 92% of children showed a modification of at least 2 behavioral patterns; after 3 months, 88% had regular bowel movements. During follow-up (range, 6 to 28 months), 48% had 2 or 3 recurrent episodes. After one year, 68% had reinforced the new behavioral patterns with resolution of the pathologic aspects. CONCLUSIONS: A multidisciplinary approach in the treatment of childhood functional constipation showed consistent therapeutic results by making rules and by equalizing family roles. J Pediatr Surg 38:819-823. 2003 Elsevier Inc. All rights reserved.


online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12720201&dopt=Abstract [PubMed - in process]



Yonsei Med J. 2003 Apr 30;44(2):265-72.
Colonic transit time in diabetic patients--comparison with healthy subjects and the effect of autonomic neuropathy.

Jung HK, Kim DY, Moon IH, Hong YS.

Digestive Disease Center, Ewha Womans University Tongdaemun Hospital, 70 Chongro 6-ga, Chongro-gu, Seoul 110-783, Korea.

Constipation and the use of laxatives are relatively common in patients with diabetes mellitus. However, the mechanisms responsible for the constipation are unclear. Even though autonomic neuropathy is regarded as one of the important mechanisms of constipation, it requires further clarification. In addition, the colonic function in diabetic patients requires further investigation. The aim of this study was to compare the colonic transit time between patients with diabetes mellitus and healthy subjects, and correlate it to the presence of cardiovascular autonomic neuropathy. The colonic transit time was measured by a noninvasive, radio-opaque marker method, and the presence of cardiovascular autonomic neuropathy was evaluated by the beat-to-beat variation and the orthostatic hypotension. Constipation was defined by the Rome II criteria. The mean total colonic transit time of the 28 diabetic patients (34.9 +/- 29.6 h, mean +/- S.D.) was significantly longer than that of the 28 healthy subjects (20.4 +/- 15.6 h, p < 0.05). Among the diabetic patients, 9/28 (32%) had constipation and 14/28 (50%) had cardiovascular autonomic neuropathy. The diabetic patients with constipation showed longer total, left and recto-sigmoid colonic transit times than those without constipation. However, the mean colonic transit time of diabetic patients with and those without cardiovascular autonomic neuropathy was similar. In conclusion, other mechanisms than the mere presence of cardiovascular autonomic neuropathy might be more relevant to the development of constipation in patients with diabetes mellitus.


online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12728467&dopt=Abstract








Hair loss is a problem in modern soceity. Examining the factors of hair growth may shed light on how hair loss might occur. How long can hair grow before it stops growing eventually if it does? Given that the hair growth rate is quite uniform and constant, somewhere between 0.3-0.5 millimeters per day, it's believed that the length of anagen, the growth phase, differs among individuals, and this is the major determinant to the maximum hair length. For some individuals, anagen may last ten years. Of course the length of the anagen is governed by genes, and the genetic background of the individuals. Non-genetic factors such as nutritional condition, weather, seasonal changes (hair may grow a bit faster during winter), taking medications, health condition may of course influence the rate of hair growth as well as hair loss. The shape of the hair, straight or curly, is dependent on the shape of the follicle. A circular or round hair follicle would generate straight hair, while the follicle with oval or elliptical shapes (in its cross-section) would produce a curly hair.














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