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Fatty acids resources:

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Klin Lab Diagn. 1998 Nov;(11):3-5.
[The oxidation resistance of heparin-precipitated blood serum beta-lipoproteins in ischemic heart disease]

[Article in Russian]

Ragino IuI, Dushkin MI.

Oxidative modification of low-density lipoproteins plays the key role in the pathogenesis of atherosclerosis. The purpose of this study was to assess oxidation resistance of serum beta-lipoproteins (beta-LP) in coronary patients in comparison with normal subjects by a simple method. The study was carried out in 37 male patients with coronary disease and type IIb dyslipoproteinemia and 48 healthy men with normolipidemia. beta-LP was isolated by precipitation in the presence of heparin. The initial level of lipid peroxides in them and their oxidation resistance during incubation in the presence of 50 microM cooper ions were assessed. The baseline content of lipid peroxides in beta-LP was two-fold increased and oxidation resistance two-fold decreased in coronary patients as against normal controls. Oxidation resistance of precipitated beta-LP in coronary patients and normal subjects was different.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10205646&dopt=Abstract

Medicina (Kaunas). 2003;39(7):707-12; quiz 713-4,717.
[Hyperglycemic hyperosmolar nonketotic syndrome]

[Article in Lithuanian]

Reingardiene D.

Clinic of Intensive Care, Kaunas University of Medicine, Eiveniu 2, 3007 Kaunas, Lithuania.

Hyperglycemic hyperosmolar nonketotic syndrome and diabetic ketoacidosis are two of the most serious acute complications of diabetes. Hyperglycemic hyperosmolar nonketotic syndrome is found mostly in type 2 diabetic patients. It is characterized by extreme dehydration and neurologic symptoms, which are related directly to the degree of hyperosmolarity. Hyperglycemic hyperosmolar nonketotic syndrome continues to be important cause of morbidity and mortality among patients with diabetes in spite of major advances in the understanding of its pathogenesis and more uniform agreement about its diagnosis and treatment. This article reviews data about precipitating factors, pathogenesis, carbohydrate, water and electrolyte metabolism in this hyperosmolar hyperglycemic state. The review discusses diagnostic procedures, laboratory evaluation, differential diagnosis and treatment: replacement of fluid and electrolytes, low-dose insulin therapy. A discussion of complications management of hyperosmolar hyperglycemia, mortality rate and prevention are included in this review.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12878827&dopt=Abstract [PubMed - in process]

Syst Parasitol. 2003 Jul;55(3):211-20.
A new entomopathogenic nematode, Steinernema anatoliense n. sp. (Rhabditida: Steinernematidae), from Turkey.

Hazir S, Stock SP, Keskin N.

Department of Biology, Faculty of Science, University of Hacettepe, 06532, Beytepe, Ankara, Turkey.

A description is given of Steinernema anatoliense n. sp. (Rhabditida: Steinernematidae), an entomopathogenic nematode isolated from soil samples collected in the locality of Kars, East Anatolia, Turkey. Cross-hybridisation, morphological and molecular studies (RFLP analysis) indicated the distinctness of S. anatoliense n. sp. from other Steinernema species. Diagnostic characters include: body length of third-stage infective juvenile (507-580 microm); lateral field pattern with 6-8 longitudinal ridges; tail shape of the first generation male with a cuticular mucro; shape of the spicules and gubernaculum; and arrangement of the genital papillae. In addition, RFLP analysis of the ITS region of rDNA shows S. anatoliense n. sp. to be distinct from 50 other Steinernema species and isolates.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12878850&dopt=Abstract [PubMed - in process]

Ophthal Plast Reconstr Surg. 2003 Jul;19(4):327-30.
Orbital osteoma arising adjacent to a foreign body.

Ma'luf RN, Ghazi NG, Zein WM, Gedeon GA, Hadi UM.

Department of Ophthalmology, American University of Beirut-Medical Center, Beirut, Lebanon.

A 27-year-old man sustained a blast injury to the face in April 1996, with a resultant foreign body at the right medial orbital wall. He refused to undergo surgical removal of the foreign body at that time and was discharged on oral antibiotics. Five years later, he presented because of recurrent attacks of swelling, redness, and pain at the right medial canthal area. A repeat computed tomography (CT) scan revealed fragmentation of the original orbital foreign body and an adjacent radiodense lesion that appeared to blend smoothly with the orbital bone from which it arose. This lesion was not present on the initial CT scan done 5 years earlier immediately following the blast. The patient was started on oral antibiotics and surgical exploration was carried out. Three fragments of the foreign body were removed in addition to the adjacent orbital lesion, which proved to be an ivory-type osteoma on histopathology. We briefly review previously suggested factors in the pathogenesis of osteoma and present further evidence in favor of both traumatic and infectious factors.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12878886&dopt=Abstract [PubMed - in process]

Alcohol Clin Exp Res. 2003 Jul;27(7):1207-12.
Role of apoptosis in alcoholic liver injury.

Ishii H, Adachi M, Fernandez-Checa JC, Cederbaum AI, Deaciuc IV, Nanji AA.

Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan. hishic.itc.keio.ac.jp

This article represents the proceedings of a symposium at the 2002 ISBRA/RSA meeting in San Francisco, USA. The organizer and chair was H. Ishii and co-chair was A.A. Nanji. The presentations were (1) Introduction: Apoptosis in alcoholic liver disease, by A. A. Nanji; (2) Mitochondria, oxidative stress and apoptosis in alcoholic liver disease, by M. Adachi; (3) Regulation of cell death by mitochondrial glutathione, by J.C. Fernandez-Checa; (4) Toxicity of ethanol in HepG2 cells that express CYP2E1, by A.I. Cederbaum; (5) Is alcohol-enhanced liver apoptosis a pathogenic factor in alcoholic liver disease? by I.V. Deaciuc.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12878930&dopt=Abstract [PubMed - in process]

Like developmental biology of any part of our body, hair growth is a complicated process. Hence the homework for modern science to yet unravel the process and mechanism to a completion. There exist a number of traditional and alternative therapeutic methods that include drugs, surgery, suppelements, and even snake oils that have been developed and used for those who lose hair. No understanding, and there is no solution. Of course, none of these approaches are perfect for all hair loss problems, especially due to the heterogeneity of the causes underlying hair losses. Most of chemical drugs and hair transplantation surgeries are accompanied by undesirable side effects.

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