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J Thorac Cardiovasc Surg. 1976 Jul;72(1):28-32.
Prosthesis endocarditis: treatment of a case occurring five years after a Rastelli-Ross operation.

Thompson J, Dirksen T, Nube M, Brom AG.

A severe staphylococcal septicemia originating from an unknown focus occurred in a 17-year-old patient who had undergone a Rastelli-Ross operation 5 years earlier. The clinical course was complicated by extensive bilateral pneumonia, diffuse intravascular coagulation, and glomerulonephritis. After 4 weeks of intensive conservative treatment, including a daily regimen of 16 Gm. of cloxacillin, the patient was operated upon for a rapidly progressive false aneurysm, which had resulted from dehiscence of the anastomosis between the prosthesis and ventricle. The excised prosthesis proved to be sterile. The postoperative course was uneventful. Cloxacillin treatment was continued for 6 months, initially parenterally and later orally. After discontinuation of therapy, no signs of infection have occurred. Right-sided intracardiac or intravascular prosthetic material may be particularly susceptible to infections originating from the body surface.

PMID:_132578 Vaccine. 2003 May 16;21(17-18):2102-5.
Invasive pneumococcal diseases in Uruguayan children: comparison between serotype distribution and conjugate vaccine formulations.

Camou T, Palacio R, Di Fabio JL, Hortal M.

National Reference Laboratory, Montevideo, Uruguay

An on-going Streptococcus pneumoniae surveillance in Uruguay furnished national information on serotype distribution of isolates from invasive infections in children </=5 years. The adequacy of 7-, 9- and 11-valent conjugate vaccine formulations was evaluated, in comparison with the prevalence of the serotypes causing disease in this target population. From 1994 to 2001, 506 isolates were submitted to the National Reference Laboratory. The heptavalent vaccine would cover 49% of the invasive isolates, while the nonavalent vaccine would potentially prevent 76% of cases. The 11-valent vaccine would increase coverage to 86%. All the serotype/groups of penicillin-resistant isolates are included in the three conjugate vaccine formulations. The available data indicate that the 9- or the 11-valent vaccines, if affordable, are the most suitable formulations for Uruguayan children.

PMID:_12706699 [PubMed - in process] Res Vet Sci. 1976 Jul;21(1):28-35.
The experimental infection of specific pathogen free lambs with Mycoplasma ovipneumoniae.

Foggie A, Jones GE, Buxton D.

Six colostrum-deprived SPF lambs inoculated endobronchially with a second passage broth culture of a Scottish strain of Mycoplasma ovipneumoniae, were killed in batches of two at seven, 14 and 28 days post-inoculation. One lamb from each batch showed macroscopic and microscopic lung lesions similar to but milder than those described for respiratory mycoplasmoses in other species of animals and exhibited minor clinical symptoms. Mycoplasma were recovered from all infected but from no control animals: five infected lambs yielded mycoplasma from lung tissue. Two lambs infected with M ovipneumoniae by endobronchial intubation were placed in contact with six other SPF lambs. M ovipneumoniae was recovered from the upper respiratory tract only of all six contact lambs, but no pathological changes were noted in their lungs. Both donor lambs yielded mycoplasma from lung tissue, but microscopic lesions were detected in only one of them, and these were minimal. No seroconversion due to the infection could be demonstrated in any of the lambs by either the indirect haemagglutination or metabolic inhibition tests.

PMID:_133436 ROFO Fortschr Geb Rontgenstr Nuklearmed. 1976 May;124(5):427-33.
[A review of the findings on chest examinations and at autopsy in surgical patients under intensive care (author's transl)]

[Article in German]

Janson R, Thelen M, Rommelsheim K, Louven B, Siege P.

The present paper deals with the findings on examination of the chest and at autopsy in 100 selected surgical patients under intensive care; of these 17% were post-traumatic, 55% had post-operative lung complications and in 28% there had been no trauma or previous operations. The accuracy of the radiological diagnosis was checked against the autopsy findings. Pneumonia and pulmonary oedema were the most common lung complications in all three groups, with an incidence of 59 to 82%, and were diagnosed with an accuracy of 92 to 95%. Other conditions which were looked for were pulmonary congestion, emboli and lung infarcts, pleural effusions, atelectasis, pulmonary haemorrhage or contusion and pneumothorax. The most common mis-diagnosis was in the demonstration of emboli and infarcts, where accuracy was only 64%. The difficulties in differential diagnosis of the radiological appearances due to these pulmonary complications are discussed.

PMID:_133894 J Med Microbiol. 1976 Aug;9(3):359-62.
A transmissible plasmid determining lactose fermentation and multiple antibiotic resistance in a strain of Klebsiella pneumoniae.

Smith HW, Parsell Z.

In a wild strain of Klebsiella pneumoniae the plasmid that determined lactose fermentation also determined resistance to chloramphenicol, ampicillin, tetracyclines, streptomycin, spectinomycin, and sulphonamides. The plasmid transferred at a very low rate to Escherichia coli K12 and Salmonella typhi. By implanting other transfer factors in the strain the rate of transfer and the recipient range were increased. Plasmid transfer from the modified strain to Salm. typhimurium and Salm. gallinarum was detected in the alimentary tract of experimentally infected chicks fed diets containing ampicillin.

PMID:_134162

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