DreamPharm Products:
Lutein-20||Herbs for headache, fever, and migraine ||
Milk thistle||Saw palmetto||
Triple B Super Vision||Garlic, Ginger, and Grapeseed Extract||
Ginseng and Ginkgo||Hair Million||
DHEA||Coenzyme Q10||
Sleep Aid herbal formula - natural sleep aid||Herbal Breath - herbs for bad breath problems.||
Weight loss herbal formula for menopause and pms||Ginkgo biloba||
Colon cleansing, Laxative||ViaVita, Lecithin for healthy liver
Fatty acids resources:
Pathogen research abs 1 || Pathogen research abs 2 || Pathogen research abs 3 || Pathogen research abs 4 || Pathogen research abs 5 ||
Hormone and endocrine research abs 1 || Hormone and endocrine research abs 2 || Hormone and endocrine research abs 3 || Hormone and endocrine research abs 4 || Hormone and endocrine research abs 5
|| Follicle and follicular cells research abs 1
|| Interferon research abs 1
|| Hemoglobin research abs
|| Stem cell research abs
Am J Clin Oncol. 2000 Oct;23(5):516-20.
Aggressive radiotherapy adjuvant to peripheral blood stem cell transplant for relapsed Hodgkin's disease.
Bogart JA, Zamkoff K, Chung CT.
Department of Radiation Oncology, SUNY Health Science Center, Syracuse, New York 13210, USA.
The role of radiotherapy in conjunction with high-dose chemotherapy and autologous bone marrow transplant for relapsed Hodgkin's disease remains to be clearly defined. Although there is substantial evidence that radiotherapy enhances local tumor control, prospective trials in the transplant setting have not been reported, and the potential toxicity of radiotherapy need to be considered. However, certain patients are at high risk of posttransplant tumor recurrence, most notably those with tumors unresponsive to pretransplant chemotherapy. We report the use of aggressive radiotherapy in three high-risk patients, including the first reported case of whole lung irradiation after a high-dose carmustine-based chemotherapy regimen. Two of these patients received repeat partial lung irradiation, including one patient with carmustine-related pulmonary toxicity. Radiotherapy (30-34.5 Gy; 1.5 Gy/fraction) was tolerated well without significant acute or late toxicity, and all patients remain disease free 40 to 62 months after irradiation without severe sequelae. We conclude that radiotherapy may be of benefit for patients at high risk of local tumor relapse, and should be considered in such cases despite potential toxicity.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11039515&dopt=Abstract
Clin Orthop. 2000 Oct;(379 Suppl):S67-70.
Mesenchymal stem cells and gene therapy.
Caplan AI.
Skeletal Research Center, Biology Department, Case Western Reserve University, Cleveland, OH 44106-7080, USA.
Multipotent human mesenchymal stem cells can be isolated from bone marrow and expanded more than 1-billion-fold in cell culture without the loss of their stem cell capacity. In addition, human mesenchymal stem cells can be transduced with genes for reporter molecules or secreted, circulating cytokines; these genes can be inserted into the genomes of mesenchymal stem cells without affecting their stem cell capacity. Thus, the stage is set for the use of mesenchymal stem cells as curative agents in genetic disorders involving skeletal tissues.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11039754&dopt=Abstract
Clin Orthop. 2000 Oct;(379 Suppl):S71-90.
Mesenchymal stem cells as vehicles for gene delivery.
Mosca JD, Hendricks JK, Buyaner D, Davis-Sproul J, Chuang LC, Majumdar MK, Chopra R, Barry F, Murphy M, Thiede MA, Junker U, Rigg RJ, Forestell SP, Bohnlein E, Storb R, Sandmaier BM.
Osiris Therapeutics, Inc, Baltimore, MD, USA.
Mesenchymal stem cells contribute to the regeneration of mesenchymal tissues such as bone, cartilage, muscle, ligament, tendon, adipose, and marrow stroma. Transduction of mesenchymal stem cells from species other than humans is required for the development of disease models in which mesenchymal stem cells-based gene delivery is evaluated. Attempts to transduce mesenchymal stem cells from some species with amphotropic retroviral vectors were unsuccessful, leading to comparative mesenchymal stem cells transductions with xenotropic and gibbon-ape leukemia virus envelope-pseudotyped retroviral vectors. Human, baboon, canine, and rat mesenchymal stem cells were transduced optimally with amphotropic vector supernatants. In contrast, sheep, goat, and pig mesenchymal stem cells showed highest transduction levels with xenotropic retroviral vector supernatant, and rabbit mesenchymal stem cells were transduced optimally with gibbon-ape-enveloped vectors. Using a myeloablative canine transplantation model and gene-marked canine mesenchymal stem cells, the biodistribution of infused and ex vivo expanded mesenchymal stem cells were examined. The majority of transduced canine mesenchymal stem cells were found in the bone marrow samples. The current study shows the use of mesenchymal stem cells as a delivery vehicle for gene transfer studies, and validates the feasibility of delivering mesenchymal stem cells to the marrow compartment for stromal regeneration after cancer-associated cytotoxic therapies.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11039755&dopt=Abstract
Immunol Lett. 2003 May 1;86(3):287-90.
Role of biomodulators and involvement of protein tyrosine kinase on stem cell migration in normal and leukaemic mice.
Law S, Maiti D, Palit A, Chaudhuri S.
Department of Haematology, Immunology and Immuno-Haematology Laboratory, School of Tropical Medicine, C.R. Avenue, 700 073, Kolkata, India
Tyrosine kinase has an important role with regard to self-renewal and as a comitogen in the movement of stem cells out of the haemopoietic stem cell pool into the progeny pool. The present investigation has an objective to evaluate the protein tyrosine kinase (PTK) activity of bone marrow derived pluripotent cells before and after application of biological response modifiers (BRMs) in normal and leukaemic mice. The PTK activity of the cytosolic fraction of bone marrow cells has been determined by the assay kit based on per-oxidase labeled substrate analog and biotin-streptavidin expression. A consequent cell population kinetic study has also been conducted. Results showed a higher activity in the cells of leukaemic mice, which under the influence of interleukin-2 (IL-2) and the non-specific BRM sheep erythrocytes (SRBC) undergo further activation. Interferon-gamma (IFN-gamma) when administered alone showed a suppressive effect and the combination of the three manifested a resultant suppression. Corresponding migration (cell population kinetics) of the bone marrow cells (BMC) also correlated well with the PTK activity of the cells concerned. The observations indicated that the pluripotent BMCs are under regulated control of the PTK activity, which can be manipulated by selective BRMs. The data also suggested the therapeutic benefit of IFN-gamma alongwith chemotherapeutics against leukaemia and that of IL-2 and SRBC during bone marrow failure.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12706533&dopt=Abstract [PubMed - in process]
Clin Orthop. 2000 Oct;(379 Suppl):S171-8.
Cartilage and bone regeneration using gene-enhanced tissue engineering.
Mason JM, Breitbart AS, Barcia M, Porti D, Pergolizzi RG, Grande DA.
Department of Research, North Shore University Hospital-New York University School of Medicine, Manhasset 11030, USA.
Joint cartilage injury remains a major problem in orthopaedics with more than 500,000 cartilage repair procedures performed yearly in the United States at a cost of hundreds of millions of dollars. No consistently reliable means to regenerate joint cartilage currently exists. The technologies of gene therapy and tissue engineering were combined using a retroviral vector to stably introduce the human bone morphogenic protein-7 complementary deoxyribonucleic acid into periosteal-derived rabbit mesenchymal stem cells. Bone morphogenic protein-7 secreting gene modified cells subsequently were expanded in monolayer culture, seeded onto polyglycolic acid grafts, implanted into a rabbit knee osteochondral defect model, and evaluated for bone and cartilage repair after 4, 8, and 12 weeks. The grafts containing bone morphogenic protein-7 gene modified cells consistently showed complete or near complete bone and articular cartilage regeneration at 8 and 12 weeks whereas the grafts from the control groups had poor repair as judged by macroscopic, histologic, and immunohistologic criteria. This is the first report of articular cartilage regeneration using a combined gene therapy and tissue engineering approach.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11039767&dopt=Abstract
The most ostensive feature that distinguishes us human from chimps and other primates is the lack of bodily hair. During evolutionary process, we have lost the majority of hair. Hair is no longer an essential part of our body, just like appendix. What little hair we still have on our scalp and a few other bodily parts is still regarded as significant for reasons other than biological necessity. Hair loss is naturally accompanied by aging process, although the extent of hair loss and the timing of onset vary widely among individuals. Thus, loss of hair and baldness is considered as a symbol of maturity or old age. Like winkles and other signs of aging, hair loss is not welcome by most people, because we don't welcome aging, and being perceived as an aging person. However, it is alopecia, or premature hair loss that especially concerns certain people.
Hair Million is a blend of Asian herbs that wards off hair loss and promotes hair growth. Of various approaches to hair restoration, Hair Million offers advantages including low cost compared with other methods or drugs, and safety, because it is made of safe and healthy herbs.
DreamPharm Online Healthy Supplements ||
Lutein ||
Natural herbal formula for hair loss problems ||